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Use of phospholipase C zeta analysis to identify candidates for artificial oocyte activation: a case series of clinical pregnancies and a proposed algorithm for patient management

Abstract:

Objective

To investigate the applicability of phospholipase C zeta (PLCζ) analysis in assisting the clinical decision-making process when considering artificial oocyte activation (AOA) for infertile males in assisted reproductive technology.

Design

Fifty-six males (43 infertile/13 fertile) were screened using our PLCζ assay.

Setting

Fertility unit/university laboratory.

Patient(s)

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
ORCID:
0000-0002-3928-1001
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Women's & Reproductive Health
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Publisher:
Elsevier Publisher's website
Journal:
Fertility and Sterility Journal website
Volume:
114
Issue:
1
Pages:
163-174
Publication date:
2020-07-01
Acceptance date:
2020-02-28
DOI:
EISSN:
1556-5653
ISSN:
0015-0282
Pubs id:
1091452
Local pid:
pubs:1091452

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