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Journal article

Clinical status and implications of antimalarial drug resistance.

Abstract:
Africa carries the greatest burden of disease caused by Plasmodium falciparum, and we can expect this burden to rise in the near future, mainly because of drug resistance. Although effective drugs are available (such as artemether-lumefantrine, mefloquine, atovaquone-proguanil and halofantrine) they are uniformly too expensive for routine use. Affordable options include chloroquine plus sulfadoxine-pyrimethamine (SP), amodiaquine (alone or in combination with SP) and chlorproguanil-dapsone. Artemisinin combination therapy may offer considerable advantages over alternative therapies, but its introduction faces considerable logistic difficulty.
Publication status:
Published

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Publisher copy:
10.1016/s1286-4579(01)01523-4

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author


Journal:
Microbes and infection / Institut Pasteur More from this journal
Volume:
4
Issue:
2
Pages:
157-164
Publication date:
2002-02-01
DOI:
EISSN:
1769-714X
ISSN:
1286-4579


Language:
English
Keywords:
Pubs id:
pubs:38153
UUID:
uuid:02ff3937-34d9-400a-aae0-73f84358fab2
Local pid:
pubs:38153
Source identifiers:
38153
Deposit date:
2012-12-19
ARK identifier:

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