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Short-chain dehydrogenases/reductases (SDR): the 2002 update.

Abstract:

Short-chain dehydrogenases/reductases (SDR) form a large, functionally heterogeneous protein family presently with about 3000 primary and about 30 3D structures deposited in databases. Despite low sequence identities between different forms (about 15-30%), the 3D structures display highly similar alpha/beta folding patterns with a central beta-sheet, typical of the Rossmann-fold. Based on distinct sequence motifs functional assignments and classifications are possible, making it possible to b...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
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Journal:
Chemico-biological interactions
Volume:
143-144
Pages:
247-253
Chapter number:
PII S0009-2797(02)00164-3
Publication date:
2003-02-05
DOI:
EISSN:
1872-7786
ISSN:
0009-2797
URN:
uuid:02e88fe8-e832-4643-a21b-c74e8df173c7
Source identifiers:
108910
Local pid:
pubs:108910

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