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The effects of novel cholinesterase inhibitors and selective muscarinic receptor agonists in tests of reference and working memory.

Abstract:

In recent years muscarinic receptor agonists and cholinesterase inhibitors have been developed for the treatment of Alzheimer's disease. We have evaluated examples from both classes of compounds in rodent tests of reference and working memory, as well as tests that are sensitive to the side-effects of these compounds. Thus, three selective muscarinic receptor partial agonists L-689,660, (M1/M3), AF102B (M1/M3) and L-687,306 (M1) and two cholinesterase inhibitors, E2020 and eptastigmine, were ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
Journal:
Behavioural brain research
Volume:
57
Issue:
2
Pages:
143-153
Publication date:
1993-11-01
DOI:
EISSN:
1872-7549
ISSN:
0166-4328
Source identifiers:
26947

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