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Cyclic oscillations of basal plasma glucose and insulin concentrations in human beings.

Abstract:

In a study of whether oscillations in plasma glucose and insulin occur in human beings, plasma samples were taken at one-minute intervals from 10 normal subjects for periods lasting between one and two hours. In five subjects the basal plasma insulin concentrations cycled regularly, with a mean period of 13 minutes and mean amplitude of 1.6 mU per liter (11.5 pmol per liter). A concurrent plasma glucose cycle was demonstrated, with a mean amplitude (after averaging to minimize random error) o...

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Publication status:
Published

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Publisher copy:
10.1056/nejm197911083011903

Authors


Matthews, DR More by this author
Turner, RC More by this author
Journal:
The New England journal of medicine
Volume:
301
Issue:
19
Pages:
1023-1027
Publication date:
1979-11-05
DOI:
EISSN:
1533-4406
ISSN:
0028-4793
URN:
uuid:02d18b27-3883-4bb3-9f99-071ae01f3e09
Source identifiers:
72931
Local pid:
pubs:72931

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