Journal article
Water and hydrophobic gates in ion channels and nanopores
- Abstract:
-
Ion channel proteins form nanopores in biological membranes which allow the passage of ions and water molecules. Hydrophobic constrictions in such pores can form gates, i.e. energetic barriers to water and ion permeation. Molecular dynamics simulations of water in ion channels may be used to assess whether a hydrophobic gate is closed (i.e. impermeable to ions) or open. If there is an energetic barrier to water permeation then it is likely that a gate will also be impermeable to ions. Simulat...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- Royal Society of Chemistry Publisher's website
- Journal:
- Faraday Discussions Journal website
- Volume:
- 209
- Pages:
- 231-247
- Publication date:
- 2018-04-16
- Acceptance date:
- 2018-02-13
- DOI:
- EISSN:
-
1364-549
- ISSN:
-
1359-6640
Item Description
- Pubs id:
-
pubs:824424
- UUID:
-
uuid:02c3e394-c074-4173-8e7d-52be78153a83
- Local pid:
- pubs:824424
- Source identifiers:
-
824424
- Deposit date:
- 2018-02-14
Terms of use
- Copyright holder:
- Rao et al
- Copyright date:
- 2018
- Notes:
- This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
- Licence:
- CC Attribution (CC BY)
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