- Abstract:
-
The short-chain dehydrogenase/reductase (SDR) superfamily now has over 47 000 members, most of which are distantly related, with typically 20-30% residue identity in pairwise comparisons, making it difficult to obtain an overview of this superfamily. We have therefore developed a family classification system, based upon hidden Markov models (HMMs). To this end, we have identified 314 SDR families, encompassing about 31,900 members. In addition, about 9700 SDR forms belong to families with too...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Publisher copy:
- 10.1111/j.1742-4658.2010.07656.x
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- Publisher:
- Wiley Publisher's website
- Journal:
- FEBS journal Journal website
- Volume:
- 277
- Issue:
- 10
- Pages:
- 2375-86
- Publication date:
- 2010-01-01
- DOI:
- ISSN:
-
1742-4658
- URN:
-
uuid:02c178d8-b220-46f4-83d8-afbb760de54b
- Local pid:
- SGC:20423462
- Copyright holder:
- Wellcome Trust, Kallberg et al., and Canadian Institutes of Health Research
- Copyright date:
- 2010
- Notes:
- Copyright © 2010 The Authors Journal compilation © 2010 FEBS
Journal article
Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models
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