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Characterisation of carbon paste electrodes for real-time amperometric monitoring of brain tissue oxygen.

Abstract:

Tissue O₂ can be monitored using a variety of electrochemical techniques and electrodes. In vitro and in vivo characterisation studies for O₂ reduction at carbon paste electrodes (CPEs) using constant potential amperometry (CPA) are presented. Cyclic voltammetry indicated that an applied potential of -650 mV is required for O₂ reduction at CPEs. High sensitivity (-1.49 ± 0.01 nA/μM), low detection limit (ca. 0.1 μM) and good linear response characteristics (R² > 0.99) were observed in cali...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
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Journal:
Journal of neuroscience methods
Volume:
195
Issue:
2
Pages:
135-142
Publication date:
2011-02-05
DOI:
EISSN:
1872-678X
ISSN:
0165-0270
URN:
uuid:02bcbbdc-5fc7-414b-b792-b0887a0fd31c
Source identifiers:
103610
Local pid:
pubs:103610

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