Journal article
Prioritizing causal genes at type 2 diabetes risk loci
- Abstract:
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Purpose of review: Genome-wide association studies (GWAS) for type 2 diabetes (T2D) risk have identified a large number of genetic loci associated with disease susceptibility. However, progress moving from association signals through causal genes to functional understanding has so far been slow, hindering clinical translation. This review discusses the benefits and limitations of emerging, unbiased approaches for prioritizing causal genes at T2D risk loci. Recent findings: Candidate causal g...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(pdf, 1.3MB)
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- Publisher copy:
- 10.1007/s11892-017-0907-y
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Authors
Funding
+ Wellcome Trust
More from this funder
Funding agency for:
Grotz, A
Grant:
SeniorFellowinBasic
BiomedicalScience(095101/Z/10/Z
200837/Z/16/Z
Bibliographic Details
- Publisher:
- Springer US Publisher's website
- Journal:
- Current Diabetes Reports Journal website
- Volume:
- 17
- Issue:
- 9
- Article number:
- 76
- Publication date:
- 2017-07-31
- Acceptance date:
- 2017-06-29
- DOI:
- EISSN:
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1539-0829
- ISSN:
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1534-4827
Item Description
- Keywords:
- Pubs id:
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pubs:710160
- UUID:
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uuid:02b419f4-3b11-492e-ba82-59c9ab9c6f37
- Local pid:
- pubs:710160
- Deposit date:
- 2017-08-02
Terms of use
- Copyright holder:
- Grotz et al
- Copyright date:
- 2017
- Notes:
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Copyright © 2017 The Authors.
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
- Licence:
- CC Attribution (CC BY)
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