Prioritizing causal genes at type 2 diabetes risk loci
Purpose of review: Genome-wide association studies (GWAS) for type 2 diabetes (T2D) risk have identified a large number of genetic loci associated with disease susceptibility. However, progress moving from association signals through causal genes to functional understanding has so far been slow, hindering clinical translation. This review discusses the benefits and limitations of emerging, unbiased approaches for prioritizing causal genes at T2D risk loci. Recent findings: Candidate causal g...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Copyright holder:
- Grotz et al
- Copyright date:
Copyright © 2017 The Authors.
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- CC Attribution (CC BY)
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