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Journal article

Population genetic structure, antibiotic resistance, capsule switching and evolution of invasive pneumococci before conjugate vaccination in Malawi

Abstract:

INTRODUCTION: Pneumococcal infections cause a high death toll in Sub Saharan Africa (SSA) but the recently rolled out pneumococcal conjugate vaccines (PCV) will reduce the disease burden. To better understand the population impact of these vaccines, comprehensive analysis of large collections of pneumococcal isolates sampled prior to vaccination is required. Here we present a population genomic study of the invasive pneumococcal isolates sampled before the implementation of PCV13 in Malawi. M...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.vaccine.2017.07.009

Authors


Publisher:
Elsevier
Journal:
Vaccine More from this journal
Volume:
35
Issue:
35B
Pages:
4594-4602
Publication date:
2017-07-12
Acceptance date:
2017-07-03
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Language:
English
Keywords:
Pubs id:
pubs:709344
UUID:
uuid:02ab0dba-b4e6-48ae-9e7f-d359d7729154
Local pid:
pubs:709344
Source identifiers:
709344
Deposit date:
2017-11-28

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