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Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial.

Abstract:

RATIONALE: To establish a new approach to investigate the physiological effects of obstructive sleep apnea (OSA), and to evaluate novel treatments, during a period of continuous positive airway pressure (CPAP) withdrawal. OBJECTIVES: To determine the effects of CPAP withdrawal. METHODS: Forty-one patients with OSA and receiving CPAP were randomized to either CPAP withdrawal (subtherapeutic CPAP), or continued CPAP, for 2 weeks. Polysomnography, sleepiness, psychomotor performance, endothelial...

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Publication status:
Published

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Publisher copy:
10.1164/rccm.201106-0964oc

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Journal:
American journal of respiratory and critical care medicine
Volume:
184
Issue:
10
Pages:
1192-1199
Publication date:
2011-11-05
DOI:
EISSN:
1535-4970
ISSN:
1073-449X
URN:
uuid:029be808-2ff1-472c-8fa1-ccb9aafb2009
Source identifiers:
170154
Local pid:
pubs:170154

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