- Abstract:
-
The best neuroprotectant for acute ischaemic stroke would always be the rapid return of oxygen and glucose to physiological levels. This is currently provided by thrombolysis which restores blood flow to the ischaemic region. The attempt to confer neuroprotection by targeting the brain parenchyma has shown promise in experimental stroke models, but has unequivocally failed to translate to the clinic. Neuroprotective therapy primarily targets the biochemical cascade that produces cell death fo...
Expand abstract - Publisher copy:
- 10.1113/jphysiol.2011.209601
-
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- Journal:
- The Journal of physiology
- Volume:
- 589
- Issue:
- Pt 17
- Pages:
- 4105-4114
- Publication date:
- 2011-09-05
- DOI:
- EISSN:
-
1469-7793
- ISSN:
-
0022-3751
- URN:
-
uuid:0268489f-f6d3-4f5a-b134-52499263f741
- Source identifiers:
-
163938
- Local pid:
- pubs:163938
- Language:
- English
- Copyright date:
- 2011
Journal article
Cerebral blood flow alteration in neuroprotection following cerebral ischaemia.
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