Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials
Background Increasing the dose intensity of cytotoxic therapy by shortening the intervals between cycles, or by giving individual drugs sequentially at full dose rather than in lower-dose concurrent treatment schedules, might enhance efficacy.
Methods To clarify the relative benefits and risks of dose-intense and standard-schedule chemotherapy in early breast cancer, we did an individual patient-level meta-analysis of trials comparing 2-weekly versu...Expand abstract
- Publication status:
- Peer review status:
- Peer reviewed
- Publisher copy:
- Pubs id:
- Local pid:
- Deposit date:
- Copyright holder:
- Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
- Copyright date:
- Copyright © 2019 The Authors. Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
- CC Attribution (CC BY)
If you are the owner of this record, you can report an update to it here: Report update to this record