Asymptotic behaviour of solutions to abstract logistic equations.

Journal article

We analyze the asymptotic behaviour of solutions of the abstract differential equation u'(t)=Au(t)-F(u(t))u(t)+f. Our results are applicable to models of structured population dynamics in which the state space consists of population densities with respect to the structure variables. In the equation the linear term A corresponds to internal processes independent of crowding, the nonlinear logistic term F corresponds to the influence of crowding, and the source term f corresponds to external effects. We analyze three separate cases and show that for each case the solutions stabilize in a way governed by the linear term. We illustrate the results with examples of models of structured population dynamics -- a model for the proliferation of cell lines with telomere shortening, a model of proliferating and quiescent cell populations, and a model for the growth of tumour cord cell populations.

Authors: Dyson, J; Villella-Bressan, R; Webb, G

• Publication status: Published
• Journal: Mathematical biosciences
• Volume: 206
• Issue: 2
• Pages: 216-232
• Publication date: 2007-04-01
• DOI: 10.1016/j.mbs.2005.08.005
• EISSN: 1879-3134
• ISSN: 0025-5564
• Language: English
• Keywords: Cell Survival; Cell Proliferation; Cell Count; Algorithms; Telomere; Logistic Models; Models, Biological; Humans; Neoplasms; Animals; Cell Aging