- Abstract:
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Background Circular RNAs (CircRNAs) are a newly appreciated class of RNAs that lack free 5′ and 3′ ends, are expressed by the thousands in diverse forms of life, and are mostly of enigmatic function. Ostensibly due to their resistance to exonucleases, circRNAs are known to be exceptionally stable. Previous work in Drosophila and mice have shown that circRNAs increase during aging in neural tissues. Results Here, we examined the global profile of circRNAs in ... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
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(pdf, 1.4mb)
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- Publisher copy:
- 10.1186/s12864-017-4386-y
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- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Genomics Journal website
- Volume:
- 19
- Pages:
- Article: 8
- Publication date:
- 2018-01-03
- Acceptance date:
- 2017-12-15
- DOI:
- ISSN:
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1471-2164
- Pubs id:
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pubs:952379
- URN:
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uri:0248b5dc-ddfd-4d74-ad78-ac898f87734d
- UUID:
-
uuid:0248b5dc-ddfd-4d74-ad78-ac898f87734d
- Local pid:
- pubs:952379
- Language:
- English
- Keywords:
- Copyright holder:
- Cortés-López et al.
- Copyright date:
- 2018
- Notes:
- Copyright © 2017 The Authors. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
Journal article
Global accumulation of circRNAs during aging in Caenorhabditis elegans
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