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Global accumulation of circRNAs during aging in Caenorhabditis elegans

Abstract:
Background Circular RNAs (CircRNAs) are a newly appreciated class of RNAs that lack free 5′ and 3′ ends, are expressed by the thousands in diverse forms of life, and are mostly of enigmatic function. Ostensibly due to their resistance to exonucleases, circRNAs are known to be exceptionally stable. Previous work in Drosophila and mice have shown that circRNAs increase during aging in neural tissues. Results Here, we examined the global profile of circRNAs in ... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s12864-017-4386-y

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Oxford college:
St Edmund Hall
Role:
Author
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Publisher:
BioMed Central Publisher's website
Journal:
BMC Genomics Journal website
Volume:
19
Article number:
8
Publication date:
2018-01-03
Acceptance date:
2017-12-15
DOI:
ISSN:
1471-2164
Pmid:
29298683
Source identifiers:
952379
Language:
English
Keywords:
Pubs id:
pubs:952379
UUID:
uuid:0248b5dc-ddfd-4d74-ad78-ac898f87734d
Local pid:
pubs:952379
Deposit date:
2018-12-16

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