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Journal article

Tapping out a mechanical code for T cell triggering

Abstract:
Mechanical forces play increasingly recognized roles in T cell receptor (TCR) signal transduction. Hu and Butte (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201511053) demonstrate that actin is required for T cells to generate forces at the TCR and that exogenous application of force can emulate these cytoskeletal forces and trigger T cell activation.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1083/jcb.201605072

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
ORCID:
0000-0003-4983-6389


Publisher:
Rockefeller University Press
Journal:
Journal of Cell Biology More from this journal
Volume:
213
Issue:
5
Pages:
501-503
Publication date:
2016-06-06
Acceptance date:
2016-05-19
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
Pmid:
27269063


Language:
English
Keywords:
Pubs id:
pubs:628474
UUID:
uuid:0231f6fe-0a36-4db1-b0e6-f18c40404025
Local pid:
pubs:628474
Source identifiers:
628474
Deposit date:
2016-11-23

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