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Increases in eotaxin-positive cells in induced sputum from atopic asthmatic subjects after inhalational allergen challenge.

Abstract:

BACKGROUND: Eosinophils are believed to be critical proinflammatory cells in airway mucosal damage in asthma. Eotaxin is a C-C chemokine with selective activity for eosinophils and basophils. Previous studies have shown increased expression of eotaxin in the airways of asthmatics at baseline. We aimed to investigate eotaxin expression during the late-phase reaction to allergen inhalation in atopic asthmatics. METHODS: Sputum induction was performed before and 24 h after inhalational allergen ...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Journal:
Allergy
Volume:
54
Issue:
7
Pages:
730-735
Publication date:
1999-07-01
DOI:
EISSN:
1398-9995
ISSN:
0105-4538
Source identifiers:
435379
Language:
English
Keywords:
Pubs id:
pubs:435379
UUID:
uuid:022bf8a3-6ab2-4de5-9463-70ca8f9157a1
Local pid:
pubs:435379
Deposit date:
2013-11-16

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