- Abstract:
-
The mechanisms by which immunologically activated mast cells stimulate the production of proinflammatory cytokines by T helper type 2 (Th2) lymphocytes were investigated in a human cell culture system. Supernatants collected from cord blood-derived mast cells after treatment with immunoglobulin E (IgE)/anti-IgE contained an activity that stimulated the production of interleukin (IL)-4, IL-5 and IL-13 (both mRNA and protein) by Th2 lymphocytes. This activity was not detected in supernatants fr...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1365-2249.2008.03871.x
-
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- Journal:
- Clinical and experimental immunology
- Volume:
- 156
- Issue:
- 1
- Pages:
- 126-133
- Publication date:
- 2009-04-05
- DOI:
- EISSN:
-
1365-2249
- ISSN:
-
0009-9104
- URN:
-
uuid:0215da34-f8b4-4335-ac85-7e047db8f68e
- Source identifiers:
-
111099
- Local pid:
- pubs:111099
- Copyright date:
- 2009
Journal article
Interaction between prostaglandin D and chemoattractant receptor-homologous molecule expressed on Th2 cells mediates cytokine production by Th2 lymphocytes in response to activated mast cells.
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