Journal article icon

Journal article

The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of the disease

Abstract:

The clinical features of relapses and progression largely define multiple sclerosis phenotypes. A relapsing course is followed by chronic progression in some 80% of cases within 2 decades. The relationship between these phases and long-term outcome remains uncertain. We have analysed these clinical features within a well-studied natural history cohort with mean follow-up of 25 years. For the entire cohort, median times to reach Disability Status Scale (DSS) 6, 8 and 10 were 12.7, 20.6 and 43....

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Publisher copy:
10.1093/brain/awh721

Authors


More by this author
Institution:
University of Western Ontario London, Ontario, Canada
Department:
Department of Clinical Neurological Sciences
More by this author
Institution:
University of Western Ontario London, Ontario, Canada
Department:
Department of Clinical Neurological Sciences
More by this author
Institution:
University of Western Ontario London, Ontario, Canada
Department:
Department of Clinical Neurological Sciences
More by this author
Institution:
Mayo Clinica, Scottsdale, AZ, USA
Department:
Department of Neurology
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Neurology
Publisher:
Oxford University Press Publisher's website
Journal:
Brain Journal website
Volume:
129
Issue:
3
Pages:
584-594
Publication date:
2006-03-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:01f96cf4-6968-4328-95a8-e0d1bb96ff3c
Local pid:
ora:4818

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP