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HLA-DR products are a subset of human Ia antigens.

Abstract:

Human Ia antigens are polymorphic cell-surface sialoglycoproteins which have restricted tissue distribution. They are bimolecular complexes of 34,000 (alpha) and 28,000 (beta) molecular weight and most of the polymorphism is found in the smaller polypeptides. They are involved in the initiation of immune responses and particular Ia antigens are associated with increased susceptibility to certain diseases. They are also the major barrier to human allogeneic tissue transplantation. Whereas sero...

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Publication status:
Published

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Publisher copy:
10.1038/301531a0

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
Role:
Author
Journal:
Nature
Volume:
301
Issue:
5900
Pages:
531-532
Publication date:
1983-02-05
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:01f50b1c-cdbf-4fe3-bee4-9390c3befd6d
Source identifiers:
42160
Local pid:
pubs:42160

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