Journal article
Pharmacokinetic-pharmacodynamic evaluation of ceftazidime continuous infusion vs intermittent bolus injection in septicaemic melioidosis.
- Abstract:
-
AIMS: Experimental studies have suggested that constant intravenous infusion would be preferable to conventional intermittent bolus administration of beta-lactam antibiotics for serious Gram-negative infections. Severe melioidosis (Burkholderia pseudomallei infection) carries a mortality over 40% despite treatment with high dose ceftazidime. The aim of this study was to measure the pharmacokinetic and pharmacodynamic effects of continuous infusion of ceftazidime vs intermittent bolus dosing ...
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Bibliographic Details
- Journal:
- British journal of clinical pharmacology
- Volume:
- 50
- Issue:
- 2
- Pages:
- 184-191
- Publication date:
- 2000-08-01
- DOI:
- EISSN:
-
1365-2125
- ISSN:
-
0306-5251
- Source identifiers:
-
95499
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:95499
- UUID:
-
uuid:01dbe694-0995-4304-9ff9-908cb5da499d
- Local pid:
- pubs:95499
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2000
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