- Abstract:
-
AIMS: Experimental studies have suggested that constant intravenous infusion would be preferable to conventional intermittent bolus administration of beta-lactam antibiotics for serious Gram-negative infections. Severe melioidosis (Burkholderia pseudomallei infection) carries a mortality over 40% despite treatment with high dose ceftazidime. The aim of this study was to measure the pharmacokinetic and pharmacodynamic effects of continuous infusion of ceftazidime vs intermittent bolus dosing ...
Expand abstract - Publisher copy:
- 10.1111/j.1365-2125.2000.00179.x
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- Journal:
- British journal of clinical pharmacology
- Volume:
- 50
- Issue:
- 2
- Pages:
- 184-191
- Publication date:
- 2000-08-05
- DOI:
- EISSN:
-
1365-2125
- ISSN:
-
0306-5251
- URN:
-
uuid:01dbe694-0995-4304-9ff9-908cb5da499d
- Source identifiers:
-
95499
- Local pid:
- pubs:95499
- Copyright date:
- 2000
Journal article
Pharmacokinetic-pharmacodynamic evaluation of ceftazidime continuous infusion vs intermittent bolus injection in septicaemic melioidosis.
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