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Journal article

High frequency spikes in long period blood cell oscillations.

Abstract:

Several hematological diseases are characterised by oscillations of various blood cell populations. Two of these are a variant of chronic myelogenous leukemia (CML) and cyclical neutropenia (CN). These oscillations typically have long periods ranging from 20 to 60 days, despite the fact that the stem cell cycling time is thought to be of the order of 2-3 days. Clinical data from humans and laboratory data from the grey collie animal model of CN is suggestive of the idea that these long period...

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Publication status:
Published

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Publisher copy:
10.1007/s00285-006-0027-9

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Journal:
Journal of mathematical biology
Volume:
53
Issue:
4
Pages:
499-519
Publication date:
2006-10-01
DOI:
EISSN:
1432-1416
ISSN:
0303-6812
Source identifiers:
202944

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