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Variation of venous admixture, SF6 shunt, PaO2, and the PaO2/FIO2 ratio with FIO2.

Abstract:

BACKGROUND: Measures of impairment of oxygenation can be affected by the inspired oxygen fraction. METHODS: We used a mathematical model of an inhomogenous lung to predict the effect of increasing inspired oxygen concentration (FIO2) on: (1) venous admixture (Qva/Qt); (2) arterial oxygen partial pressure (PaO2); (3) the PaO2/FIO2 index of hypoxaemia; and (4) sulphur hexafluoride (SF6) retention (often taken to be true right-to-left shunt). This model predicts whether or not atelectasis will o...

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Publication status:
Published

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Publisher copy:
10.1093/bja/88.6.771

Authors


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Institution:
University of Oxford
Department:
Oxford, MPLS, Computer Science
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Computer Science
Role:
Author
Journal:
British journal of anaesthesia
Volume:
88
Issue:
6
Pages:
771-778
Publication date:
2002-06-05
DOI:
EISSN:
1471-6771
ISSN:
0007-0912
URN:
uuid:01c510e9-5b96-410f-b0c8-9e08081ffe0a
Source identifiers:
242471
Local pid:
pubs:242471

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