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Antimalarial drug resistance.

Abstract:

Malaria, the most prevalent and most pernicious parasitic disease of humans, is estimated to kill between one and two million people, mainly children, each year. Resistance has emerged to all classes of antimalarial drugs except the artemisinins and is responsible for a recent increase in malaria-related mortality, particularly in Africa. The de novo emergence of resistance can be prevented by the use of antimalarial drug combinations. Artemisinin-derivative combinations are particularly effe...

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Publisher copy:
10.1172/jci21682

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Role:
Author
Journal:
The Journal of clinical investigation
Volume:
113
Issue:
8
Pages:
1084-1092
Publication date:
2004-04-05
DOI:
EISSN:
1558-8238
ISSN:
0021-9738
URN:
uuid:01c1b711-2cce-473b-8fee-164629a9658e
Source identifiers:
95493
Local pid:
pubs:95493

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