Journal article
Stop antibiotics when you feel better? Opportunities, challenges and research directions
- Abstract:
- Shortening standard antibiotic courses and stopping antibiotics when patients feel better are two ways to reduce exposure to antibiotics in the community, and decrease the risks of antimicrobial resistance and antibiotic side effects. While evidence shows that shorter antibiotic treatments are non-inferior to longer ones for infections that benefit from antibiotics, shorter courses still represent average treatment durations that might be suboptimal for some. In contrast, stopping antibiotics based on improvement or resolution of symptoms might help personalize antibiotic treatment to individual patients and help reduce unnecessary exposure. Yet, many challenges need addressing before we can consider this approach evidence-based and implement it in practice. In this viewpoint article, we set out the main evidence gaps and avenues for future research.
- Publication status:
- Published
- Peer review status:
- Reviewed (other)
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(Preview, Version of record, pdf, 242.7KB, Terms of use)
-
- Publisher copy:
- 10.1093/jacamr/dlae147
Authors
- Publisher:
- Oxford University Press
- Journal:
- JAC-Antimicrobial Resistance More from this journal
- Volume:
- 6
- Issue:
- 5
- Article number:
- dlae147
- Publication date:
- 2024-09-09
- Acceptance date:
- 2024-08-26
- DOI:
- EISSN:
-
2632-1823
- Language:
-
English
- Pubs id:
-
2023411
- Local pid:
-
pubs:2023411
- Deposit date:
-
2024-08-27
Terms of use
- Copyright holder:
- Borek et al
- Copyright date:
- 2024
- Rights statement:
- © The Author(s) 2024. Published by Oxford University Press on behalf of British Society for Antimicrobial Chemotherapy. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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