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Journal article

Evolution and emergence of novel human infections

Abstract:

Some zoomotic pathogens cause sporadic infection in humans but rarely propagate further, while others have succeeeded in overcoming the species barrier and becoming established in the human population. Adaptation, driven by selection pressure in human hosts, can play a significant role in allowing pathogens to cross this species barrier. Here we use a simple mathematical model to study potential epidemiological markers of adaptation. We ask: under what circumstances could ongoing adaptation b...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1098/rspb.2009.1059

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Institution:
University of Oxford
Department:
Institute for Emerging Infections,James Martin 21st Century School
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Institute for Emerging Infections,James Martin 21st Century School
Role:
Author
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Funding agency for:
N. Arinaminpathy
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Funding agency for:
A. R. McLean
Publisher:
Royal Society Publisher's website
Journal:
Proceedings of the Royal Society B Journal website
Volume:
276
Issue:
1675
Pages:
3937-3943
Publication date:
2009-11-05
DOI:
EISSN:
1471-2954
URN:
uuid:019db51c-5a4d-43c4-a7a0-f063edf0b93c
Local pid:
ora:3567
Language:
English
Keywords:
Subjects:

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