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Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis.

Abstract:

Antibody-secreting hybrid cells have been derived from a fusion between mouse myeloma cells and spleen cells from a mouse immunized with membrane from human tonsil lymphocyte preparations. Hybrids secreting antibodies to cell surface antigens were detected by assaying culture supernatants for antibody binding to human tonsil cells. Six different antibodies (called W6/1, /28, /32, /34, /45 and /46 were analyzed. These were either against antigens of wide tissue distribution (W6/32, /34, and /4...

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Publication status:
Published

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Journal:
Cell
Volume:
14
Issue:
1
Pages:
9-20
Publication date:
1978-05-05
DOI:
EISSN:
1097-4172
ISSN:
0092-8674
URN:
uuid:01980fc8-21e1-4454-960c-4e0b17a30f9f
Source identifiers:
487593
Local pid:
pubs:487593

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