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Isolation of the pyrrolizidine alkaloid 1-epialexine from Castanospermum australe

Abstract:
The Australian leguminous tree Castanospermum australe contains the anti-viral glucose analogue indolizidine alkaloid castanospermine. As the result of a search for new bioactive carbohydrate-like compounds we now report the isolation of the novel polyhydroxylated pyrrolizidine alkaloid, 1-epialexine, from the leaves and stems of C. australe. 1-Epialexine is a weak inhibitor of β-mannosidase from Cellullomonas fimi. © 2010 Phytochemical Society of Europe.
Publication status:
Published

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Publisher copy:
10.1016/j.phytol.2010.04.003

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author


Journal:
PHYTOCHEMISTRY LETTERS More from this journal
Volume:
3
Issue:
3
Pages:
133-135
Publication date:
2010-09-20
DOI:
ISSN:
1874-3900


Language:
English
Keywords:
Pubs id:
pubs:116952
UUID:
uuid:01924a9d-f007-41e0-9b62-65c42c484242
Local pid:
pubs:116952
Source identifiers:
116952
Deposit date:
2012-12-19
ARK identifier:

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