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Base and copper(I) catalyzed Mannich, alkyne hydroamination cascades for the direct synthesis of 2-methylenepyrrolidines.

Abstract:
An efficient, simple-to-perform, one-pot reaction cascade to 2-methylenepyrrolidines from p-toluenesulfonyl protected imines and propargylated malonates under a combination of base and copper(I) catalysis is reported.
Publication status:
Published

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Publisher copy:
10.1039/b905629g

Authors

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author


Journal:
Chemical Communications More from this journal
Issue:
26
Pages:
3916-3918
Publication date:
2009-07-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345


Language:
English
Keywords:
Pubs id:
pubs:41233
UUID:
uuid:018ac80a-5ab0-4b28-9dad-0de73c3397a2
Local pid:
pubs:41233
Source identifiers:
41233
Deposit date:
2012-12-19
ARK identifier:

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