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Determining the minimum clinically important differences for outcomes in the DOMINO trial.

Abstract:

BACKGROUND: Although less likely to be reported in clinical trials than expressions of the statistical significance of differences in outcomes, whether or not a treatment has delivered a specified minimum clinically important difference (MCID) is also relevant to patients and their caregivers and doctors. Many dementia treatment randomised controlled trials (RCTs) have not reported MCIDs and, where they have been done, observed differences have not reached these. METHODS: As part of the devel...

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Publication status:
Published

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Publisher copy:
10.1002/gps.2607

Authors


Phillips, P More by this author
Johnson, T More by this author
O'Brien, J More by this author
Sheehan, B More by this author
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Journal:
International journal of geriatric psychiatry
Volume:
26
Issue:
8
Pages:
812-817
Publication date:
2011-08-05
DOI:
EISSN:
1099-1166
ISSN:
0885-6230
URN:
uuid:01478e33-38bf-4f2b-a8af-21ae59010481
Source identifiers:
167708
Local pid:
pubs:167708

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