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Intravenous iron delivers a sustained (8-week) lowering of pulmonary artery pressure during exercise in healthy older humans

Abstract:

In older individuals, pulmonary artery pressure rises markedly during exercise, probably due in part to increased pulmonary vascular resistance and in part to an increase in left-heart filling pressure. Older individuals also show more marked pulmonary vascular response to hypoxia at rest. Treatment with intra-venous iron reduces the rise in pulmonary artery pressure observed during hypoxia. Here, we test the hypothesis that intravenous iron administration may also attenuate the rise in pulmo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.14814/phy2.14164

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology, Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology, Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology, Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology, Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Physiology, Anatomy & Genetics
Role:
Author
Publisher:
Wiley
Journal:
Physiological Reports More from this journal
Volume:
7
Issue:
13
Article number:
e14164
Publication date:
2019-07-03
Acceptance date:
2019-06-15
DOI:
ISSN:
2051-817X
Keywords:
Pubs id:
pubs:1014762
UUID:
uuid:013ec932-0a12-4ee8-a160-374b14472ed9
Local pid:
pubs:1014762
Source identifiers:
1014762
Deposit date:
2019-06-17

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