Evolving resistance to artemisinin-based compounds threatens to derail attempts to control malaria. Resistance has been confirmed in western Cambodia and has recently emerged in western Thailand, but is absent from neighboring Laos. Artemisinin resistance results in reduced parasite clearance rates (CRs) after treatment. We used a two-phase strategy to identify genome region(s) underlying this ongoing selective event. Geographical differentiation and haplotype structure at 6969 polymorphic si...Expand abstract
- Publisher copy:
- Copyright date:
- PMCID: PMC3355473
A major genome region underlying artemisinin resistance in malaria.
If you are the owner of this record, you can report an update to it here: Report update to this record