On the foundations of cancer modelling: Selected topics, speculations, and perspectives

Journal article

Abstract:: This paper presents a critical review of selected topics related to the modelling of cancer onset, evolution and growth, with the aim of illustrating, to a wide applied mathematical readership, some of the novel mathematical problems in the field. This review attempts to capture, from the appropriate literature, the main issues involved in the modelling of phenomena related to cancer dynamics at all scales which characterise this highly complex system: from the molecular scale up to that of tissue. The last part of the paper discusses the challenge of developing a mathematical biological theory of tumour onset and evolution. © 2008 World Scientific Publishing Company.

Journal:: MATHEMATICAL MODELS and METHODS IN APPLIED SCIENCES More from this journal
Volume:: 18
Issue:: 4
Pages:: 593-646
Publication date:: 2008-04-01
DOI:: 10.1142/S0218202508002796
EISSN:: 1793-6314
ISSN:: 0218-2025

Language:: English
Keywords:: complexity in biology

living systems

multiscale modelling

cancer modelling
Pubs id:: pubs:11198
UUID:: uuid:00cf945a-73f6-466b-9aa9-5cbbfea01568
Local pid:: pubs:11198
Source identifiers:: 11198
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_00cf945a73f6466b9aa95cbbfea01568

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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