Journal article icon

Journal article

Genome-wide analysis of selection on the malaria parasite Plasmodium falciparum in West African populations of differing infection endemicity.

Abstract:

Locally varying selection on pathogens may be due to differences in drug pressure, host immunity, transmission opportunities between hosts, or the intensity of between-genotype competition within hosts. Highly recombining populations of the human malaria parasite Plasmodium falciparum throughout West Africa are closely related, as gene flow is relatively unrestricted in this endemic region, but markedly varying ecology and transmission intensity should cause distinct local selective pressures...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/molbev/msu106

Authors


Mobegi, VA More by this author
Amambua-Ngwa, A More by this author
Expand authors...
Publisher:
Oxford University Press
Journal:
Molecular biology and evolution
Volume:
31
Issue:
6
Pages:
1490-1499
Publication date:
2014-06-05
DOI:
EISSN:
1537-1719
ISSN:
0737-4038
URN:
uuid:00b97f1e-02ce-42d3-a136-6d81233d25a6
Source identifiers:
457862
Local pid:
pubs:457862

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP