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Variant Creutzfeldt-Jakob disease: an unfolding epidemic of misfolded proteins.

Abstract:

Variant Creutzfeldt-Jakob disease (vCJD) is an emerging infectious disease believed to be the human manifestation of bovine spongiform encephalopathy (BSE). Variant CJD belongs to a family of human and animal diseases called transmissible spongiform encephalopathies (TSE). The pathogenesis of TSE is not fully understood, but a modified form of a normal cellular protein plays a central role. Current measures to control vCJD aim to prevent transmission of the infectious agent from animals to hu...

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Publication status:
Published

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Journal:
Journal of paediatrics and child health
Volume:
38
Issue:
6
Pages:
539-542
Publication date:
2002-12-05
DOI:
EISSN:
1440-1754
ISSN:
1034-4810
URN:
uuid:00af1bad-852c-4cad-996e-6e8b3b976242
Source identifiers:
68072
Local pid:
pubs:68072

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