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Ancorinosides B-D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele

Abstract:
Ancorinosides B-D were isolated from the marine sponge Penares sollasi Thiele as inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).1 Their structures were elucidated to be tetramic acid glycosides related to ancorinoside A by spectroscopic and chemical methods. Ancorinosides B-D inhibited MT1-MMP with IC50 values of 180-500 μg/mL. © 2001 Elsevier Science Ltd.
Publication status:
Published

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Publisher copy:
10.1016/S0040-4020(00)01128-5

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author


Journal:
TETRAHEDRON More from this journal
Volume:
57
Issue:
7
Pages:
1229-1234
Publication date:
2001-02-11
DOI:
ISSN:
0040-4020


Language:
English
Keywords:
Pubs id:
pubs:225570
UUID:
uuid:00ae24a1-c045-4176-97aa-5f9d0d03bae1
Local pid:
pubs:225570
Source identifiers:
225570
Deposit date:
2012-12-19
ARK identifier:

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