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Ancorinosides B-D, inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP), from the marine sponge Penares sollasi Thiele

Abstract:
Ancorinosides B-D were isolated from the marine sponge Penares sollasi Thiele as inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).1 Their structures were elucidated to be tetramic acid glycosides related to ancorinoside A by spectroscopic and chemical methods. Ancorinosides B-D inhibited MT1-MMP with IC50 values of 180-500 μg/mL. © 2001 Elsevier Science Ltd.
Publication status:
Published

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Authors


Matsunaga, S More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
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Journal:
TETRAHEDRON
Volume:
57
Issue:
7
Pages:
1229-1234
Publication date:
2001-02-11
DOI:
ISSN:
0040-4020
URN:
uuid:00ae24a1-c045-4176-97aa-5f9d0d03bae1
Source identifiers:
225570
Local pid:
pubs:225570

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