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Journal article

The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of the disease.

Abstract:

The clinical features of relapses and progression largely define multiple sclerosis phenotypes. A relapsing course is followed by chronic progression in some 80% of cases within 2 decades. The relationship between these phases and long-term outcome remains uncertain. We have analysed these clinical features within a well-studied natural history cohort with mean follow-up of 25 years. For the entire cohort, median times to reach Disability Status Scale (DSS) 6, 8 and 10 were 12.7, 20.6 and 43....

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Publication status:
Published

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Publisher copy:
10.1093/brain/awh721

Authors


Kremenchutzky, M More by this author
Baskerville, J More by this author
Wingerchuk, DM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, WTC Human Genetics
Journal:
Brain : a journal of neurology
Volume:
129
Issue:
Pt 3
Pages:
584-594
Publication date:
2006-03-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:00a83820-b5e7-4b1f-9ecc-d767e4cf140c
Source identifiers:
33352
Local pid:
pubs:33352

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