Journal article icon

Journal article

MHC class I-restricted cytotoxic lymphocyte responses induced by enterotoxin-based mucosal adjuvants.

Abstract:

The ability of enterotoxin-based mucosal adjuvants to induce CD8+ MHC class I-restricted CTL responses to a codelivered bystander Ag was examined. Escherichia coli heat-labile toxin (LT), or derivatives of LT carrying mutations in the A subunit (LTR72, LTK63), were tested in parallel with cholera toxin (CT) or a fusion protein consisting of the A1 subunit of CT fused to the Ig binding domain of Staphylococcus aureus protein A (called CTA1-DD). Intranasal (i.n.) immunization of C57BL/6 mice wi...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Role:
Author
Expand authors...
Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
163
Issue:
12
Pages:
6502-6510
Publication date:
1999-12-05
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:009b8652-ff9a-4bfa-8e01-1597addb7692
Source identifiers:
98242
Local pid:
pubs:98242

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP