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Synthesis and Antibacterial Activity of Bicyclic Lactam-Lactones

Abstract:
The synthesis of a lactam-lactone bicyclic system containing a pyroglutamate subunit proceeds to give the fused lactone system, which is favoured over the spirocyclic lactone alternative. These systems display no or weak antibacterial activity against the test organisms S. aureus and E. coli. © Georg Thieme Verlag Stuttgart · New York.
Publication status:
Published

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Publisher copy:
10.1055/s-0030-1261197

Authors

More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Inorganic Chemistry
Role:
Author


Journal:
SYNLETT More from this journal
Volume:
2011
Issue:
15
Pages:
2181-2184
Publication date:
2011-09-01
DOI:
EISSN:
1437-2096
ISSN:
0936-5214


Language:
English
Keywords:
Pubs id:
pubs:177271
UUID:
uuid:00997013-02f4-41b3-93fd-7919ac6f7454
Local pid:
pubs:177271
Source identifiers:
177271
Deposit date:
2012-12-19
ARK identifier:

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