The genome sequence of Schizosaccharomyces pombe.

Journal article

We have sequenced and annotated the genome of fission yeast (Schizosaccharomyces pombe), which contains the smallest number of protein-coding genes yet recorded for a eukaryote: 4,824. The centromeres are between 35 and 110 kilobases (kb) and contain related repeats including a highly conserved 1.8-kb element. Regions upstream of genes are longer than in budding yeast (Saccharomyces cerevisiae), possibly reflecting more-extended control regions. Some 43% of the genes contain introns, of which...

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Authors: Wood, V; Gwilliam, R; Rajandream, M; Lyne, M; Lyne, R

• Publication status: Published
• Journal: Nature
• Volume: 415
• Issue: 6874
• Pages: 871-880
• Publication date: 2002-02-01
• DOI: 10.1038/nature724
• EISSN: 1476-4687
• ISSN: 0028-0836
• Language: English
• Keywords: Eukaryotic Cells; Genome, Fungal; Sequence Analysis, DNA; Research Support, Non-U.S. Gov't; Base Sequence; Protein Structure, Tertiary; Fungal Proteins; Centromere; DNA, Fungal; Humans; Schizosaccharomyces; Chromosomes, Fungal; Introns; Chromosome Mapping; Genetic Diseases, Inborn; Gene Duplication