- Abstract:
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Background:CLL is a chronic disease that often progresses slowly from a precursor stage, monoclonal B-cell lymphocytosis (MBL), and that can remain undiagnosed for a long time. Methods:Within the European EPIC cohort, we measured pre-diagnostic plasma sCD23 for 179 individuals who eventually were diagnosed with CLL and an equal number of matched control subjects who remained free of cancer. Results: In a very large proportion of CLL patients plasma sCD23 was clearly elevated 7 or more years b...
Expand abstract - Publisher copy:
- 10.1158/1055-9965.EPI-14-1107
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- Journal:
- Cancer epidemiology, biomarkers and prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
- Publication date:
- 2014-12-05
- DOI:
- EISSN:
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1538-7755
- ISSN:
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1055-9965
- URN:
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uuid:00229531-5f97-4c63-80e7-d1fc47e60a47
- Source identifiers:
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503302
- Local pid:
- pubs:503302
- Language:
- English
- Copyright date:
- 2014
Journal article
Lag-times between lympho-proliferative disorder and clinical diagnosis of chronic lymphocytic leukemia (CLL): a prospective analysis using plasma soluble CD23.
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