Journal article icon

Journal article

Antitumor effects and normal tissue toxicity of 111In-labeled epidermal growth factor administered to athymic mice bearing epidermal growth factor receptor-positive human breast cancer xenografts.

Abstract:

UNLABELLED: The epidermal growth factor receptor (EGFR) is an attractive target for the design of radiotherapeutic agents for breast cancer because it is present on almost all estrogen receptor-negative, hormone-resistant tumors with a poor prognosis. In this study, we describe the antitumor effects and normal tissue toxicity of the novel Auger electron-emitting radiopharmaceutical (111)In-labeled diethylenetriaminepentaacetic acid-human epidermal growth factor ((111)In-DTPA-hEGF) administer...

Expand abstract
Publication status:
Published

Actions


Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Oncology
Role:
Author
Journal:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Volume:
44
Issue:
9
Pages:
1469-1478
Publication date:
2003-09-05
EISSN:
1535-5667
ISSN:
0161-5505
URN:
uuid:00221e93-cfae-4966-9418-f7e123b3ffdf
Source identifiers:
130909
Local pid:
pubs:130909

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP