Journal article

ASYMMETRIC-SYNTHESIS OF R-BETA-AMINO BUTANOIC ACID AND S-BETA-TYROSINE - HOMOCHIRAL LITHIUM AMIDE EQUIVALENTS FOR MICHAEL ADDITIONS TO ALPHA,BETA-UNSATURATED ESTERS

Abstract:: Michael addition of the lithium amide derived from R-N-(α-methylbenzyl)benzylamine to benzyl E-crotonate is highly stereoselective (95% d.e.) giving after debenzylation and crystallisation homochiral R-β-amino butanoic acid. A similar addition to methyl E-(p-benzyloxy)cinnamate is completely stereoselective giving after debenzylation and acid hydrolysis homochiral S-β-tyrosine as its HCl salt. © 1993.

Publication status:: Published

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APA Style

Davies, S., & Ichihara, O. (1991). ASYMMETRIC-SYNTHESIS OF R-BETA-AMINO BUTANOIC ACID AND S-BETA-TYROSINE - HOMOCHIRAL LITHIUM AMIDE EQUIVALENTS FOR MICHAEL ADDITIONS TO ALPHA,BETA-UNSATURATED ESTERS. TETRAHEDRON-ASYMMETRY, 2(3), 183–186.

MLA Style

Davies, S, and O Ichihara. “ASYMMETRIC-SYNTHESIS OF R-BETA-AMINO BUTANOIC ACID AND S-BETA-TYROSINE - HOMOCHIRAL LITHIUM AMIDE EQUIVALENTS FOR MICHAEL ADDITIONS TO ALPHA,BETA-UNSATURATED ESTERS.” TETRAHEDRON-ASYMMETRY, vol. 2, no. 3, 1991, pp. 183–86.

Chicago Style

Davies, S, and O Ichihara. 1991. “ASYMMETRIC-SYNTHESIS OF R-BETA-AMINO BUTANOIC ACID AND S-BETA-TYROSINE - HOMOCHIRAL LITHIUM AMIDE EQUIVALENTS FOR MICHAEL ADDITIONS TO ALPHA,BETA-UNSATURATED ESTERS.” TETRAHEDRON-ASYMMETRY 2 (3): 183–86.
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Publisher copy:: 10.1016/S0957-4166(00)82354-X

Authors

+ Davies, S More by this author

Institution:: University of Oxford
Division:: MPLS
Department:: Chemistry
Sub department:: Organic Chemistry
Role:: Author

+ Ichihara, O More by this author

Role:: Author

Journal:: TETRAHEDRON-ASYMMETRY More from this journal
Volume:: 2
Issue:: 3
Pages:: 183-186
Publication date:: 1991-01-01
DOI:: 10.1016/S0957-4166(00)82354-X
EISSN:: 1362-511X
ISSN:: 0957-4166

Pubs id:: pubs:110747
UUID:: uuid:346bcda7-4229-4f95-84e6-b21d1f3ce1c4
Local pid:: pubs:110747
Source identifiers:: 110747
Deposit date:: 2012-12-19
ARK identifier:: ark:/29072/ora_346bcda742294f9584e6b21d1f3ce1c4

Terms of use

Copyright date:: 1991

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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