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Association of the DRD2 gene Taq1A polymorphism and alcoholism: a meta-analysis of case-control studies and evidence of publication bias.

Abstract:

We investigated the association of the dopamine D2 receptor (DRD2) Taq1A polymorphism and alcoholism, using meta-analytic techniques, and specifically undertook an investigation of possible publication bias. Potential publication bias represents a genuine risk to the integrity of published research, but its impact has rarely been documented. We observed a small effect of the DRD2 Taq1A polymorphism on risk of alcoholism, indicating increased alcoholism in individuals possessing the A1 allele ...

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Publication status:
Published

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Publisher copy:
10.1038/sj.mp.4001938

Authors


Munafo, MR More by this author
Matheson, IJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Journal:
Molecular psychiatry
Volume:
12
Issue:
5
Pages:
454-461
Publication date:
2007-05-05
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
URN:
uuid:ffef2de0-4bd1-44dd-b914-97536ee9d89b
Source identifiers:
40324
Local pid:
pubs:40324

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