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Recent advances in incretin-based therapies.

Abstract:

The global burden of type 2 diabetes is growing. Traditional therapies are suboptimal and there is a clear unmet need for treatments that offer effective glucose control while addressing the comorbid factors associated with diabetes, such as obesity and risk of cardiovascular disease, without the fear of hypoglycaemia. Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors offer a novel way of reducing hyperglycaemia by targeting the incretin system. This review provi...

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Publication status:
Published

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Authors


Russell-Jones, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM, Biomedical Research Centre
Journal:
Clinical endocrinology
Volume:
77
Issue:
4
Pages:
489-499
Publication date:
2012-10-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:ffc1bcec-041a-46e2-84f9-66afa8320a31
Source identifiers:
342333
Local pid:
pubs:342333

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