Journal article icon

Journal article

Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex

Abstract:

Two-component signal transduction pathways comprising histidine protein kinases (HPKs) and their response regulators (RRs) are widely used to control bacterial responses to environmental challenges. Some bacteria have over 150 different two-component pathways, and the specificity of the phosphotransfer reactions within these systems is tightly controlled to prevent unwanted crosstalk. One of the best understood two-component signalling pathways is the chemotaxis pathway. Here, we present the ...

Expand abstract

Actions


Access Document


Authors


Journal:
PLoS Biology
Volume:
8
Issue:
2
Publication date:
2010-02-05
DOI:
EISSN:
1545-7885
ISSN:
1544-9173
URN:
uuid:ffbbc969-566a-4d0a-b031-94cf32fde920
Source identifiers:
79815
Local pid:
pubs:79815
Language:
English

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP