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Oral bisphosphonates and risk of cancer of oesophagus, stomach, and colorectum: case-control analysis within a UK primary care cohort

Abstract:

Objective: To examine the hypothesis that risk of oesophageal, but not of gastric or colorectal, cancer is increased in users of oral bisphosphonates.

Design: Nested case-control analysis within a primary care cohort of about 6 million people in the UK, with prospectively recorded information on prescribing of bisphosphonates.

Setting: UK General Practice Research Database cohort.

Participants: Men and women aged 40 years or over - 2954 with oesophageal cancer, 2018 with...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1136/bmj.c4444

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Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Cancer Epidemiology Unit
Role:
Author
More by this author
Institution:
Medicines and Healthcare products Regulatory Agency, Pharmacoepidemiology Research Unit, London
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Cancer Epidemiology Unit
Role:
Author

Contributors

Institution:
University of Oxford
Department:
Medical Sciences Division - Clinical Medicine,Nuffield Department of - Cancer Epidemiology Unit
Medical Research Council More from this funder
Cancer Research UK More from this funder
Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Journal website
Volume:
341
Pages:
Article: c4444
Publication date:
2010-09-05
DOI:
EISSN:
1756-1833
URN:
uuid:ff7d3eac-f736-4b37-af40-5e608e1739ac
Local pid:
ora:5704
Language:
English
Keywords:
Subjects:

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