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Journal article

A genome-scale metabolic model accurately predicts fluxes in central carbon metabolism under stress conditions.

Abstract:

Flux is a key measure of the metabolic phenotype. Recently, complete (genome-scale) metabolic network models have been established for Arabidopsis (Arabidopsis thaliana), and flux distributions have been predicted using constraints-based modeling and optimization algorithms such as linear programming. While these models are useful for investigating possible flux states under different metabolic scenarios, it is not clear how close the predicted flux distributions are to those occurring in viv...

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Publication status:
Published

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Publisher copy:
10.1104/pp.110.158535

Authors


Williams, TC More by this author
Poolman, MG More by this author
Howden, AJ More by this author
Schwarzlander, M More by this author
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Journal:
Plant physiology
Volume:
154
Issue:
1
Pages:
311-323
Publication date:
2010-09-05
DOI:
EISSN:
1532-2548
ISSN:
0032-0889
URN:
uuid:ff70e425-a1aa-411e-a3fd-3ac0d4667cd5
Source identifiers:
65264
Local pid:
pubs:65264

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