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Choosing between small, likely rewards and large, unlikely rewards activates inferior and orbital prefrontal cortex.

Abstract:

Patients sustaining lesions of the orbital prefrontal cortex (PFC) exhibit marked impairments in the performance of laboratory-based gambling, or risk-taking, tasks, suggesting that this part of the human PFC contributes to decision-making cognition. However, to date, little is known about the particular regions of the orbital cortex that participate in this function. In the present study, eight healthy volunteers were scanned, using H(2)(15)0 PET technology, while performing a novel computer...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Middleton, HC More by this author
Williams, EJ More by this author
Pickard, JD More by this author
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Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
19
Issue:
20
Pages:
9029-9038
Publication date:
1999-10-05
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:ff6ab421-278e-433e-9734-9095be54d459
Source identifiers:
223170
Local pid:
pubs:223170

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