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Modelling the role of angiogenesis and vasculogenesis in solid tumour growth.

Abstract:

Recent experimental evidence suggests that vasculogenesis may play an important role in tumour vascularisation. While angiogenesis involves the proliferation and migration of endothelial cells (ECs) in pre-existing vessels, vasculogenesis involves the mobilisation of bone-marrow-derived endothelial progenitor cells (EPCs) into the bloodstream. Once blood-borne, EPCs home in on the tumour site, where subsequently they may differentiate into ECs and form vascular structures. In this paper, we d...

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Publication status:
Published

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Publisher copy:
10.1007/s11538-007-9253-6

Authors


Stamper, IJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Mathematical Inst
Journal:
Bulletin of mathematical biology
Volume:
69
Issue:
8
Pages:
2737-2772
Publication date:
2007-11-05
DOI:
EISSN:
1522-9602
ISSN:
0092-8240
URN:
uuid:ff5e482c-19ad-42f3-a210-1805ede3be48
Source identifiers:
25666
Local pid:
pubs:25666

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